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A spatiotemporal characterization of the effect of p53 phosphorylation on its interaction with MDM2
The interaction of p53 and MDM2 is modulated by the phosphorylation of p53. This mechanism is key to activating p53, yet its molecular determinants are not fully understood. To study the spatiotemporal characteristics of this molecular process we carried out Brownian dynamics simulations of the inte...
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| Publicado no: | Cell Cycle |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353223/ https://ncbi.nlm.nih.gov/pubmed/25584963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.989043 |
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