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Mutant IDH1: An immunotherapeutic target in tumors
The discovery of driver mutations in cancers has raised interest in their suitability as immunotherapeutic targets. A recent study demonstrates that a point mutation in isocitrate dehydrogenase 1 (IDH1R132H), expressed in gliomas and other tumors, is presented on human MHC class II and induces a mut...
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| Publicado en: | Oncoimmunology |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353168/ https://ncbi.nlm.nih.gov/pubmed/25964867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.974392 |
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