Interleukin-6 receptor and its ligand interleukin-6 are opposite markers for survival and infiltration with mature myeloid cells in ovarian cancer

An increased level of interleukin-6 (IL-6) in epithelial ovarian cancer (EOC) is correlated with a worse prognosis. IL-6 stimulates tumor-growth and inflammation. We investigated the intricate interaction between the IL-6 signaling pathway and tumor-infiltrating myeloid cells (TIMs) to determine the...

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Udgivet i:Oncoimmunology
Main Authors: Wouters, MCA, Dijkgraaf, EM, Kuijjer, ML, Jordanova, ES, Hollema, H, Welters, MJP, van der Hoeven, JJM, Daemen, T, Kroep, JR, Nijman, HW, van der Burg, SH
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353164/
https://ncbi.nlm.nih.gov/pubmed/25964862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.962397
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