Sex differences in aging, life span and spontaneous tumorigenesis in 129/Sv mice neonatally exposed to metformin

The perinatal (prenatal and early neonatal) period is a critical stage for hypothalamic programming of sexual differentiation as well as for the development of energy and metabolic homeostasis. We hypothesized that neonatal treatment with antidiabetic drug biguanide metformin would positively modify...

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Bibliografiska uppgifter
I publikationen:Cell Cycle
Huvudupphovsmän: Anisimov, Vladimir N, Popovich, Irina G, Zabezhinski, Mark A, Egormin, Peter A, Yurova, Maria N, Semenchenko, Anna V, Tyndyk, Margarita L, Panchenko, Andrey V, Trashkov, Alexandr P, Vasiliev, Andrey G, Khaitsev, Nikolai V
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2015
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Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353070/
https://ncbi.nlm.nih.gov/pubmed/25483062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.973308
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