Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice

Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia are important factors both in aging and in the development of cancer. It is possible that the life-prolonging effects of calorie restriction are due to decreasing IGF-1 levels. A search of pharmacological modulator...

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Detalhes bibliográficos
Main Authors: Anisimov, Vladimir N., Piskunova, Tatiana S., Popovich, Irina G., Zabezhinski, Mark A., Tyndyk, Margarita L., Egormin, Peter A., Yurova, Maria N., Rosenfeld, Svetlana V., Semenchenko, Anna V., Kovalenko, Irina G., Poroshina, Tatiana E., Berstein, Lev M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034183/
https://ncbi.nlm.nih.gov/pubmed/21164223
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