Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice

Studies in mammals have led to the suggestion that hyperglycemia and hyperinsulinemia are important factors both in aging and in the development of cancer. It is possible that the life-prolonging effects of calorie restriction are due to decreasing IGF-1 levels. A search of pharmacological modulator...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Anisimov, Vladimir N., Piskunova, Tatiana S., Popovich, Irina G., Zabezhinski, Mark A., Tyndyk, Margarita L., Egormin, Peter A., Yurova, Maria N., Rosenfeld, Svetlana V., Semenchenko, Anna V., Kovalenko, Irina G., Poroshina, Tatiana E., Berstein, Lev M.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2010
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034183/
https://ncbi.nlm.nih.gov/pubmed/21164223
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