Differential Control of Heme Reactivity in Alpha and Beta Subunits of Hemoglobin: A Combined Raman Spectroscopic and Computational Study

[Image: see text] The use of hybrid hemoglobin (Hb), with mesoheme substituted for protoheme, allows separate monitoring of the α or β hemes along the allosteric pathway. Using resonance Raman (rR) spectroscopy in silica gel, which greatly slows protein motions, we have observed that the Fe–histidin...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Am Chem Soc
Hoofdauteurs: Jones, Eric M., Monza, Emanuele, Balakrishnan, Gurusamy, Blouin, George C., Mak, Piotr J., Zhu, Qianhong, Kincaid, James R., Guallar, Victor, Spiro, Thomas G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2014
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353013/
https://ncbi.nlm.nih.gov/pubmed/24991732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja503328a
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items