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Linking Conformation Change to Hemoglobin Activation Via Chain-Selective Time-resolved Resonance Raman Spectroscopy on Protoheme/Mesoheme Hybrids

Time-resolved Resonance Raman spectra are reported for Hb tetramers, in which the αand β chains are selectively substituted with mesoheme. The Soret absorbtion band shift in meso- relative to proto-heme permits chain-selective excitation of heme RR spectra. The evolution of these spectra following H...

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Detalhes bibliográficos
Main Authors: Balakrishnan, Gurusamy, Ibrahim, Mohammed, Mak, Piotr J., Hata, Jessica, Kincaid, James R., Spiro, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880192/
https://ncbi.nlm.nih.gov/pubmed/19288145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-009-0487-7
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