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Subunit-Selective Interrogation of CO Recombination in Carbonmonoxy Hemoglobin by Isotope-Edited Time-resolved Resonance Raman Spectroscopy

Hemoglobin is an allosteric tetrameric protein made up of αβ hetero-dimers. The α and β chains are similar, but are chemically and structurally distinct. To investigate dynamical differences between the chains, we have prepared tetramers in which the chains are isotopically distinguishable, via reco...

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書誌詳細
主要な著者: Balakrishnan, Gurusamy, Zhao, Xiaojie, Podstawska, Edyta, Proniewicz, Leonard M., Kincaid, James R., Spiro, Thomas G.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722936/
https://ncbi.nlm.nih.gov/pubmed/19245215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802190f
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