Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation

Polycomb Group (PcG) proteins maintain transcriptional repression throughout development, mostly by regulating chromatin structure. Polycomb Repressive Complex 2 (PRC2), a component of the Polycomb machinery, is responsible for the methylation of histone H3 lysine 27 (H3K27me2/3). Jarid2 was previou...

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Veröffentlicht in:Mol Cell
Hauptverfasser: Sanulli, Serena, Justin, Neil, Teissandier, Aurélie, Ancelin, Katia, Portoso, Manuela, Caron, Matthieu, Michaud, Audrey, Lombard, Berangère, da Rocha, Simao T., Offer, John, Loew, Damarys, Servant, Nicolas, Wassef, Michel, Burlina, Fabienne, Gamblin, Steve J., Heard, Edith, Margueron, Raphaël
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352895/
https://ncbi.nlm.nih.gov/pubmed/25620564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.12.020
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