RING finger protein 121 facilitates the degradation and membrane localization of voltage-gated sodium channels

Following their synthesis in the endoplasmic reticulum (ER), voltage-gated sodium channels (Na(V)) are transported to the membranes of excitable cells, where they often cluster, such as at the axon initial segment of neurons. Although the mechanisms by which Na(V) channels form and maintain clusters...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ogino, Kazutoyo, Low, Sean E., Yamada, Kenta, Saint-Amant, Louis, Zhou, Weibin, Muto, Akira, Asakawa, Kazuhide, Nakai, Junichi, Kawakami, Koichi, Kuwada, John Y., Hirata, Hiromi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352840/
https://ncbi.nlm.nih.gov/pubmed/25691753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414002112
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