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RING finger protein 121 facilitates the degradation and membrane localization of voltage-gated sodium channels
Following their synthesis in the endoplasmic reticulum (ER), voltage-gated sodium channels (Na(V)) are transported to the membranes of excitable cells, where they often cluster, such as at the axon initial segment of neurons. Although the mechanisms by which Na(V) channels form and maintain clusters...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352840/ https://ncbi.nlm.nih.gov/pubmed/25691753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414002112 |
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