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Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b

The molecular and physiological basis of the touch-unresponsive zebrafish mutant fakir has remained elusive. Here we report that the fakir phenotype is caused by a missense mutation in the gene encoding voltage-gated calcium channel 2.1b (CACNA1Ab). Injection of RNA encoding wild-type CaV2.1 restore...

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Bibliografiska uppgifter
Huvudupphovsmän: Low, Sean E., Woods, Ian G., Lachance, Mathieu, Ryan, Joel, Schier, Alexander F., Saint-Amant, Louis
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434603/
https://ncbi.nlm.nih.gov/pubmed/22490555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00839.2011
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