Dendritic cell SIRT1–HIF1α axis programs the differentiation of CD4(+) T cells through IL-12 and TGF-β1

The differentiation of naive CD4(+) T cells into distinct lineages plays critical roles in mediating adaptive immunity or maintaining immune tolerance. In addition to being a first line of defense, the innate immune system also actively instructs adaptive immunity through antigen presentation and im...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Liu, Guangwei, Bi, Yujing, Xue, Lixiang, Zhang, Yan, Yang, Hui, Chen, Xi, Lu, Yun, Zhang, Zhengguo, Liu, Huanrong, Wang, Xiao, Wang, Ruoning, Chu, Yiwei, Yang, Ruifu
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352801/
https://ncbi.nlm.nih.gov/pubmed/25730867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420419112
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