The Calcineurin-NFAT Axis Controls Allograft Immunity in Myeloid-Derived Suppressor Cells through Reprogramming T Cell Differentiation

While cyclosporine (CsA) inhibits calcineurin and is highly effective in prolonging rejection for transplantation patients, the immunological mechanisms remain unknown. Herein, the role of calcineurin signaling was investigated in a mouse allogeneic skin transplantation model. The calcineurin inhibi...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Wang, Xiao, Bi, Yujing, Xue, Lixiang, Liao, Jiongbo, Chen, Xi, Lu, Yun, Zhang, Zhengguo, Wang, Jian, Liu, Huanrong, Yang, Hui, Liu, Guangwei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285420/
https://ncbi.nlm.nih.gov/pubmed/25452304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01251-14
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