The Calcineurin-NFAT Axis Controls Allograft Immunity in Myeloid-Derived Suppressor Cells through Reprogramming T Cell Differentiation

While cyclosporine (CsA) inhibits calcineurin and is highly effective in prolonging rejection for transplantation patients, the immunological mechanisms remain unknown. Herein, the role of calcineurin signaling was investigated in a mouse allogeneic skin transplantation model. The calcineurin inhibi...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Main Authors: Wang, Xiao, Bi, Yujing, Xue, Lixiang, Liao, Jiongbo, Chen, Xi, Lu, Yun, Zhang, Zhengguo, Wang, Jian, Liu, Huanrong, Yang, Hui, Liu, Guangwei
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285420/
https://ncbi.nlm.nih.gov/pubmed/25452304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01251-14
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