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Genomic landscape of pediatric adrenocortical tumors

Pediatric adrenocortical carcinoma is a rare malignancy with poor prognosis. Here we analyze 37 adrenocortical tumors (ACTs) by whole genome, whole exome and/or transcriptome sequencing. Most cases (91%) show loss of heterozygosity (LOH) of chromosome 11p, with uniform selection against the maternal...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Pinto, Emilia M., Chen, Xiang, Easton, John, Finkelstein, David, Liu, Zhifa, Pounds, Stanley, Rodriguez-Galindo, Carlos, Lund, Troy C., Mardis, Elaine R., Wilson, Richard K., Boggs, Kristy, Yergeau, Donald, Cheng, Jinjun, Mulder, Heather L., Manne, Jayanthi, Jenkins, Jesse, Mastellaro, Maria J., Figueiredo, Bonald C., Dyer, Michael A., Pappo, Alberto, Zhang, Jinghui, Downing, James R., Ribeiro, Raul C., Zambetti, Gerard P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352712/
https://ncbi.nlm.nih.gov/pubmed/25743702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7302
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