OR02-1 DNA Methylation Profiling in Pediatric Adrenocortical Tumors Reveals Distinct Methylation Signatures with Prognostic Significance: A Report from the International Pediatric Adrenocortical Tumor Registry

Pediatric adrenocortical tumors (ACTs) are heterogeneous and have a poor prognosis. Overall survival is around 60%. In pediatric ACT that is managed only with surgery, features associated with adverse outcome include age greater than 3 years, non-functioning tumors, and metastatic (Stage IV) or resi...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: Clay, Michael, Pinto, Emilia, Cline, Cynthia, Tran, Quynh, Lin, Tong, Wu, Huiyun, Azzato, Elizabeth, Pappo, Alberto, Dyer, Michael, Pounds, Stanley, Ellison, David, Zambetti, Gerard, Orr, Brent, Ribeiro, Raul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2019
Schlagworte:
Adrenal
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554806/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR02-1
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