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Structure-Function Analysis of VapB4 Antitoxin Identifies Critical Features of a Minimal VapC4 Toxin-Binding Module

Bacterial toxin-antitoxin systems play a critical role in the regulation of gene expression, leading to developmental changes, reversible dormancy, and cell death. Type II toxin-antitoxin pairs, composed of protein toxins and antitoxins, exist in nearly all bacteria and are classified into six group...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Jin, Guangze, Pavelka, Martin S., Butler, J. Scott
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352670/
https://ncbi.nlm.nih.gov/pubmed/25622615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02508-14
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