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A Novel Carboline Derivative Inhibits Nitric Oxide Formation in Macrophages Independent of Effects on Tumor Necrosis Factor α and Interleukin-1β Expression

Neuropathic pain is a maladaptive immune response to peripheral nerve injury that causes a chronic painful condition refractory to most analgesics. Nitric oxide (NO), which is produced by nitric oxide synthases (NOSs), has been implicated as a key factor in the pathogenesis of neuropathic pain. β-Ca...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Pharmacol Exp Ther
Päätekijät: Grodzki, Ana Cristina G., Poola, Bhaskar, Pasupuleti, Nagarekha, Nantz, Michael H., Lein, Pamela J., Gorin, Fredric
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352593/
https://ncbi.nlm.nih.gov/pubmed/25538105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.220186
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