Production of tumor necrosis factor and nitric oxide by macrophages infected with live and dead mycobacteria and their suppression by an interleukin-10-secreting recombinant.

We have analyzed mycobacterium-induced cytokine secretion in the J774A.1 macrophage-like cell line. Tumor necrosis factor alpha (TNF-alpha) was preferentially induced by live organisms, both slow and rapid growing. Expression of interleukin-10 by a recombinant strain of Mycobacterium smegmatis cause...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Marshall, B G, Chambers, M A, Wangoo, A, Shaw, R J, Young, D B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9125582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.65.5.1931-1935.1997
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