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A Cell-Permeant Amiloride Derivative Induces Caspase-Independent, AIF-Mediated Programmed Necrotic Death of Breast Cancer Cells

Amiloride is a potassium-sparing diuretic that has been used as an anti-kaliuretic for the chronic management of hypertension and heart failure. Several studies have identified a potential anti-cancer role for amiloride, however the mechanisms underlying its anti-tumor effects remain to be fully del...

詳細記述

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書誌詳細
主要な著者: Leon, Leonardo J., Pasupuleti, Nagarekha, Gorin, Fredric, Carraway, Kermit L.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639988/
https://ncbi.nlm.nih.gov/pubmed/23646172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063038
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