Increased eculizumab requirements during pregnancy in a patient with paroxysmal nocturnal hemoglobinuria: case report and review of the literature

Paroxysmal nocturnal hemoglobinuria (PNH) results from reduced complement regulatory proteins on hematopoietic cells, predisposing patients to intravascular hemolysis, thrombophilia, and cytopenias. Women diagnosed in pregnancy can experience significant maternofetal complications. Trials of eculizu...

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Bibliografiske detaljer
Udgivet i:Clin Case Rep
Main Authors: Patriquin, Christopher, Leber, Brian
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Case Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352359/
https://ncbi.nlm.nih.gov/pubmed/25767703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.161
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