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Increased eculizumab requirements during pregnancy in a patient with paroxysmal nocturnal hemoglobinuria: case report and review of the literature

Paroxysmal nocturnal hemoglobinuria (PNH) results from reduced complement regulatory proteins on hematopoietic cells, predisposing patients to intravascular hemolysis, thrombophilia, and cytopenias. Women diagnosed in pregnancy can experience significant maternofetal complications. Trials of eculizu...

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Podrobná bibliografie
Vydáno v:Clin Case Rep
Hlavní autoři: Patriquin, Christopher, Leber, Brian
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352359/
https://ncbi.nlm.nih.gov/pubmed/25767703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.161
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