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Increased eculizumab requirements during pregnancy in a patient with paroxysmal nocturnal hemoglobinuria: case report and review of the literature

Paroxysmal nocturnal hemoglobinuria (PNH) results from reduced complement regulatory proteins on hematopoietic cells, predisposing patients to intravascular hemolysis, thrombophilia, and cytopenias. Women diagnosed in pregnancy can experience significant maternofetal complications. Trials of eculizu...

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Опубликовано в: :Clin Case Rep
Главные авторы: Patriquin, Christopher, Leber, Brian
Формат: Artigo
Язык:Inglês
Опубликовано: BlackWell Publishing Ltd 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352359/
https://ncbi.nlm.nih.gov/pubmed/25767703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ccr3.161
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