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Expression of drug transporters in human kidney: impact of sex, age, and ethnicity

BACKGROUND: Differences in expression of drug transporters in human kidney contribute to changes in pharmacokinetics and toxicokinetics of a variety of drug compounds. The basal expression levels of genes involved in drug transport processes in the kidney introduces differences in bioavailability, d...

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Détails bibliographiques
Publié dans:Biol Sex Differ
Auteurs principaux: Joseph, Stancy, Nicolson, Tamara J, Hammons, George, Word, Beverly, Green-Knox, Bridgett, Lyn-Cook, Beverly
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352278/
https://ncbi.nlm.nih.gov/pubmed/25750709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-015-0020-3
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