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Effect of cigarette smoke condensate on gene promoter methylation in human lung cells

BACKGROUND: In lung cancer, an association between tobacco smoking and promoter DNA hypermethylation has been demonstrated for several genes. However, underlying mechanisms for promoter hypermethylation in tobacco-induced cancer are yet to be fully established. METHODS: Promoter methylation was eval...

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Detalhes bibliográficos
Main Authors: Lyn-Cook, Lascelles, Word, Beverly, George, Nysia, Lyn-Cook, Beverly, Hammons, George
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160916/
https://ncbi.nlm.nih.gov/pubmed/25214829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1617-9625-12-15
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