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ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?

Genetic polymorphisms in ABC (ATP-binding cassette) transporter genes are associated with differential responses to chemotherapy in various cancers including pancreatic cancer. In this study, four SNPs in the ABCB1, ABCC1, and ABCG2 genes were investigated in normal and pancreatic cancerous specimen...

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Autors principals: Pang, Li, Word, Beverly, Xu, Joshua, Wang, Honggang, Hammons, George, Huang, Shiew-Mei, Lyn-Cook, Beverly
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026978/
https://ncbi.nlm.nih.gov/pubmed/24883056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/414931
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