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ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?

Genetic polymorphisms in ABC (ATP-binding cassette) transporter genes are associated with differential responses to chemotherapy in various cancers including pancreatic cancer. In this study, four SNPs in the ABCB1, ABCC1, and ABCG2 genes were investigated in normal and pancreatic cancerous specimen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pang, Li, Word, Beverly, Xu, Joshua, Wang, Honggang, Hammons, George, Huang, Shiew-Mei, Lyn-Cook, Beverly
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026978/
https://ncbi.nlm.nih.gov/pubmed/24883056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/414931
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