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The matrix metalloproteinase inhibitor RS-130830 attenuates brain injury in experimental pneumococcal meningitis
BACKGROUND: Pneumococcal meningitis (PM) is characterized by high mortality and morbidity including long-term neurofunctional deficits. Neuropathological correlates of these sequelae are apoptosis in the hippocampal dentate gyrus and necrosis in the cortex. Matrix metalloproteinases (MMPs) play a cr...
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| Publicado no: | J Neuroinflammation |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352253/ https://ncbi.nlm.nih.gov/pubmed/25890041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0257-0 |
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