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Functional consequences of age-related morphologic changes to pyramidal neurons of the rhesus monkey prefrontal cortex

Layer 3 (L3) pyramidal neurons in the lateral prefrontal cortex (LPFC) of rhesus monkeys exhibit dendritic regression, spine loss and increased action potential (AP) firing rates during normal aging. The relationship between these structural and functional alterations, if any, is unknown. To address...

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Detalhes bibliográficos
Publicado no:J Comput Neurosci
Main Authors: Coskren, Patrick J., Luebke, Jennifer I., Kabaso, Doron, Wearne, Susan L., Yadav, Aniruddha, Rumbell, Timothy, Hof, Patrick R., Weaver, Christina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352129/
https://ncbi.nlm.nih.gov/pubmed/25527184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10827-014-0541-5
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