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Functional consequences of age-related morphologic changes to pyramidal neurons of the rhesus monkey prefrontal cortex

Layer 3 (L3) pyramidal neurons in the lateral prefrontal cortex (LPFC) of rhesus monkeys exhibit dendritic regression, spine loss and increased action potential (AP) firing rates during normal aging. The relationship between these structural and functional alterations, if any, is unknown. To address...

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Publicat a:J Comput Neurosci
Autors principals: Coskren, Patrick J., Luebke, Jennifer I., Kabaso, Doron, Wearne, Susan L., Yadav, Aniruddha, Rumbell, Timothy, Hof, Patrick R., Weaver, Christina M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352129/
https://ncbi.nlm.nih.gov/pubmed/25527184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10827-014-0541-5
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