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Functional consequences of age-related morphologic changes to pyramidal neurons of the rhesus monkey prefrontal cortex

Layer 3 (L3) pyramidal neurons in the lateral prefrontal cortex (LPFC) of rhesus monkeys exhibit dendritic regression, spine loss and increased action potential (AP) firing rates during normal aging. The relationship between these structural and functional alterations, if any, is unknown. To address...

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Détails bibliographiques
Publié dans:J Comput Neurosci
Auteurs principaux: Coskren, Patrick J., Luebke, Jennifer I., Kabaso, Doron, Wearne, Susan L., Yadav, Aniruddha, Rumbell, Timothy, Hof, Patrick R., Weaver, Christina M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352129/
https://ncbi.nlm.nih.gov/pubmed/25527184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10827-014-0541-5
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