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All tangled up: how cells direct, manage and exploit topoisomerase function
Topoisomerases are complex molecular machines that modulate DNA topology to maintain chromosome superstructure and integrity. Although capable of stand-alone activity in vitro, topoisomerases frequently are linked to larger pathways and systems that resolve specific DNA superstructures and intermedi...
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Publicado no: | Nat Rev Mol Cell Biol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351964/ https://ncbi.nlm.nih.gov/pubmed/22108601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3228 |
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