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Sphingosine-1-Phosphate Induces the Migration of Thyroid Follicular Carcinoma Cells through the MicroRNA-17/PTK6/ERK1/2 Pathway

Sphingosine-1-phosphate (S1P) is a bioactive lipid known to play a role in tumorigenesis and cancer progression. However, the molecular mechanisms of S1P regulated migration of papillary thyroid cancer cells are still unknown. In this study, we showed that S1P induced PTK6 mRNA and protein expressio...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Zhao, Shitao, Li, Jincheng
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351951/
https://ncbi.nlm.nih.gov/pubmed/25748447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119148
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