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Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 signaling is required for migration of naive human T cells from the thymus to the periphery

BACKGROUND: The mechanisms that govern the egress of mature thymocytes from the human thymus to the periphery remain understudied yet are of utmost importance to the field of basic immunology, as well as T-cell reconstitution in various immunodeficiencies. We examined the expression and function of...

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Publicado en:J Allergy Clin Immunol
Autores principales: Resop, Rachel S., Douaisi, Marc, Craft, Joshua, Jachimowski, Loes C. M., Blom, Bianca, Uittenbogaart, Christel H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007110/
https://ncbi.nlm.nih.gov/pubmed/27056271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.12.1339
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