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Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 signaling is required for migration of naive human T cells from the thymus to the periphery

BACKGROUND: The mechanisms that govern the egress of mature thymocytes from the human thymus to the periphery remain understudied yet are of utmost importance to the field of basic immunology, as well as T-cell reconstitution in various immunodeficiencies. We examined the expression and function of...

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Опубликовано в: :J Allergy Clin Immunol
Главные авторы: Resop, Rachel S., Douaisi, Marc, Craft, Joshua, Jachimowski, Loes C. M., Blom, Bianca, Uittenbogaart, Christel H.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007110/
https://ncbi.nlm.nih.gov/pubmed/27056271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.12.1339
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