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IFN-α Is Constitutively Expressed in the Human Thymus, but Not in Peripheral Lymphoid Organs

Type I interferons have been typically studied for their effects in the context of bacterial or viral infections. However in this report, we provide evidence that Interferon-alpha (IFN-α) expressing cells are present in the thymus in the absence of infection. We show that pDC express the highest lev...

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Bibliografiske detaljer
Main Authors: Colantonio, Arnaud D., Epeldegui, Marta, Jesiak, Maria, Jachimowski, Loes, Blom, Bianca, Uittenbogaart, Christel H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164161/
https://ncbi.nlm.nih.gov/pubmed/21904619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024252
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