Sphingosine-1-Phosphate as a Regulator of Hypoxia-Induced Factor-1α in Thyroid Follicular Carcinoma Cells

Sphingosine-1-phosphate (S1P) is a bioactive lipid, which regulates several cancer-related processes including migration and angiogenesis. We have previously shown S1P to induce migration of follicular ML-1 thyroid cancer cells. Hypoxia-induced factor-1 (HIF-1) is an oxygen-sensitive transcription f...

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Главные авторы: Kalhori, Veronica, Kemppainen, Kati, Asghar, Muhammad Yasir, Bergelin, Nina, Jaakkola, Panu, Törnquist, Kid
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688870/
https://ncbi.nlm.nih.gov/pubmed/23824493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066189
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