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OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer

BACKGROUND: OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a deubiquitinating enzyme (DUB) that belongs to the OTU (ovarian tumor) superfamily. The aim of this study was to clarify the role of OTUB1 in colorectal cancer (CRC) and to identify the mechanism underlying its function. METHOD...

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Τόπος έκδοσης:	Mol Cancer
Κύριοι συγγραφείς:	Zhou, Yi, Wu, Jiangxue, Fu, Xiang, Du, Wuying, Zhou, Ling, Meng, Xiangqi, Yu, Hongyan, Lin, Jiaxin, Ye, Wen, Liu, Jiani, Peng, Hui, Liu, Ran-yi, Pan, Changchuan, Huang, Wenlin
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BioMed Central 2014
Θέματα:	Research
Διαθέσιμο Online:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4351937/ https://ncbi.nlm.nih.gov/pubmed/25431208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-258
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OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer

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