OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer

BACKGROUND: OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a deubiquitinating enzyme (DUB) that belongs to the OTU (ovarian tumor) superfamily. The aim of this study was to clarify the role of OTUB1 in colorectal cancer (CRC) and to identify the mechanism underlying its function. METHOD...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cancer
Egile Nagusiak: Zhou, Yi, Wu, Jiangxue, Fu, Xiang, Du, Wuying, Zhou, Ling, Meng, Xiangqi, Yu, Hongyan, Lin, Jiaxin, Ye, Wen, Liu, Jiani, Peng, Hui, Liu, Ran-yi, Pan, Changchuan, Huang, Wenlin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351937/
https://ncbi.nlm.nih.gov/pubmed/25431208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-258
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