OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer

BACKGROUND: OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a deubiquitinating enzyme (DUB) that belongs to the OTU (ovarian tumor) superfamily. The aim of this study was to clarify the role of OTUB1 in colorectal cancer (CRC) and to identify the mechanism underlying its function. METHOD...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cancer
Prif Awduron: Zhou, Yi, Wu, Jiangxue, Fu, Xiang, Du, Wuying, Zhou, Ling, Meng, Xiangqi, Yu, Hongyan, Lin, Jiaxin, Ye, Wen, Liu, Jiani, Peng, Hui, Liu, Ran-yi, Pan, Changchuan, Huang, Wenlin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351937/
https://ncbi.nlm.nih.gov/pubmed/25431208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-258
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