OTUB1 promotes metastasis and serves as a marker of poor prognosis in colorectal cancer

BACKGROUND: OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a deubiquitinating enzyme (DUB) that belongs to the OTU (ovarian tumor) superfamily. The aim of this study was to clarify the role of OTUB1 in colorectal cancer (CRC) and to identify the mechanism underlying its function. METHOD...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Zhou, Yi, Wu, Jiangxue, Fu, Xiang, Du, Wuying, Zhou, Ling, Meng, Xiangqi, Yu, Hongyan, Lin, Jiaxin, Ye, Wen, Liu, Jiani, Peng, Hui, Liu, Ran-yi, Pan, Changchuan, Huang, Wenlin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351937/
https://ncbi.nlm.nih.gov/pubmed/25431208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-258
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