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Structures of Pup Ligase PafA and Depupylase Dop of the Prokaryotic Ubiquitin-like Modification Pathway

Pupylation is a post-translational protein modification occurring in mycobacteria and other actinobacteria that is functionally analogous to ubiquitination. Here, we report the crystal structures of the modification enzymes involved in this pathway, the Pup ligase PafA and the depupylase/deamidase D...

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Publicat a:Nat Commun
Autors principals: Özcelik, Dennis, Barandun, Jonas, Schmitz, Nikolaus, Sutter, Markus, Guth, Ethan, Damberger, Fred F., Allain, Frédéric H.-T., Ban, Nenad, Weber-Ban, Eilika
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351746/
https://ncbi.nlm.nih.gov/pubmed/22910360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2009
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