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Structures of Pup Ligase PafA and Depupylase Dop of the Prokaryotic Ubiquitin-like Modification Pathway

Pupylation is a post-translational protein modification occurring in mycobacteria and other actinobacteria that is functionally analogous to ubiquitination. Here, we report the crystal structures of the modification enzymes involved in this pathway, the Pup ligase PafA and the depupylase/deamidase D...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Özcelik, Dennis, Barandun, Jonas, Schmitz, Nikolaus, Sutter, Markus, Guth, Ethan, Damberger, Fred F., Allain, Frédéric H.-T., Ban, Nenad, Weber-Ban, Eilika
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351746/
https://ncbi.nlm.nih.gov/pubmed/22910360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2009
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