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Structures of Pup Ligase PafA and Depupylase Dop of the Prokaryotic Ubiquitin-like Modification Pathway

Pupylation is a post-translational protein modification occurring in mycobacteria and other actinobacteria that is functionally analogous to ubiquitination. Here, we report the crystal structures of the modification enzymes involved in this pathway, the Pup ligase PafA and the depupylase/deamidase D...

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發表在:Nat Commun
Main Authors: Özcelik, Dennis, Barandun, Jonas, Schmitz, Nikolaus, Sutter, Markus, Guth, Ethan, Damberger, Fred F., Allain, Frédéric H.-T., Ban, Nenad, Weber-Ban, Eilika
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351746/
https://ncbi.nlm.nih.gov/pubmed/22910360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2009
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