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Phosphatidylinositol 3-kinase, Class 2 beta (PI3KC2β) isoform contributes to neuroblastoma tumorigenesis
Phosphatidylinositol 3-kinases (PI3Ks) play important roles in human tumorigenesis. Activation of the PI3K target AKT is frequent in neuroblastoma (NB) and correlates with poor prognosis. PI3K pan-inhibitors reduce NB tumor formation but present severe toxicity, which limits their therapeutic potent...
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| Izdano u: | Cancer Lett |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351744/ https://ncbi.nlm.nih.gov/pubmed/25622909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.01.026 |
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