ErbB3 ablation impairs phosphatidylinositol 3-kinase (PI3K)/AKT-dependent mammary tumorigenesis

The ErbB receptor family member ErbB3 has been implicated in breast cancer growth but it has yet to be determined whether its disruption is therapeutically valuable. In a mouse model of mammary carcinoma driven by the polyomavirus middle T (PyVmT) oncogene, the ErbB2 tyrosine kinase inhibitor lapati...

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Bibliografiske detaljer
Main Authors: Cook, Rebecca S., Garrett, Joan T., Sánchez, Violeta, Stanford, Jamie C., Young, Christian, Chakravarty, Anindita, Rinehart, Cammie, Zhang, Yixian, Wu, Yaming, Greenberger, Lee, Horak, Ivan D., Arteaga, Carlos L.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204389/
https://ncbi.nlm.nih.gov/pubmed/21482676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3775
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