Marked therapeutic efficacy of a novel polyethylene glycol-SN38 conjugate, EZN-2208, in xenograft models of B-cell non-Hodgkin’s lymphoma

Por Sapra, Puja, Kraft, Patricia, Mehlig, Mary, Malaby, Jennifer, Zhao, Hong, Greenberger, Lee M., Horak, Ivan D.
Publicado em 2009

EZN-2208 (PEG-SN38) Overcomes ABCG2-Mediated Topotecan Resistance in BRCA1-Deficient Mouse Mammary Tumors

Por Zander, Serge A. L., Sol, Wendy, Greenberger, Lee, Zhang, Yixian, van Tellingen, Olaf, Jonkers, Jos, Borst, Piet, Rottenberg, Sven
Publicado em 2012

Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effects

Por Sapra, Puja, Kraft, Patricia, Pastorino, Fabio, Ribatti, Domenico, Dumble, Melissa, Mehlig, Mary, Wang, Maoliang, Ponzoni, Mirco, Greenberger, Lee M., Horak, Ivan D.
Publicado em 2011

ErbB3 ablation impairs phosphatidylinositol 3-kinase (PI3K)/AKT-dependent mammary tumorigenesis

Por Cook, Rebecca S., Garrett, Joan T., Sánchez, Violeta, Stanford, Jamie C., Young, Christian, Chakravarty, Anindita, Rinehart, Cammie, Zhang, Yixian, Wu, Yaming, Greenberger, Lee, Horak, Ivan D., Arteaga, Carlos L.
Publicado em 2011