Mutagenic effects induced by the attack of NO(2) radical to the guanine-cytosine base pair

We investigate the attack of the nitrogen dioxide radical (NO(•)(2)) to the guanine—cytosine (GC) base pair and the subsequent tautomeric reactions able to induce mutations, by means of density functional theory (DFT) calculations. The conducted simulations allow us to identify the most reactive sit...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Chem
Egile Nagusiak: Cerón-Carrasco, José P., Requena, Alberto, Zúñiga, José, Jacquemin, Denis
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2015
Gaiak:
Chemistry
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351615/
https://ncbi.nlm.nih.gov/pubmed/25798437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2015.00013
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