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Mutagenic effects induced by the attack of NO(2) radical to the guanine-cytosine base pair

We investigate the attack of the nitrogen dioxide radical (NO(•)(2)) to the guanine—cytosine (GC) base pair and the subsequent tautomeric reactions able to induce mutations, by means of density functional theory (DFT) calculations. The conducted simulations allow us to identify the most reactive sit...

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Опубликовано в: :Front Chem
Главные авторы: Cerón-Carrasco, José P., Requena, Alberto, Zúñiga, José, Jacquemin, Denis
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351615/
https://ncbi.nlm.nih.gov/pubmed/25798437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2015.00013
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