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(G–H)(•)–C and G–(C–H)(•) radicals derived from the guanine·cytosine base pair cause DNA subunit lesions

The radicals generated by the homolytic cleavage of an X–H bond from the guanine·cytosine (G·C) base pair were studied by using carefully calibrated theoretical methods. The gradient-corrected density functional B3LYP was applied in conjunction with double-ζ plus polarization and diffuse function ba...

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Detalhes bibliográficos
Main Authors: Bera, Partha Pratim, Schaefer, Henry F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1100756/
https://ncbi.nlm.nih.gov/pubmed/15814617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408644102
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