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Density Functional Study of the Influence of C5 Cytosine Substitution in Base Pairs with Guanine

The present study employs density-functional electronic structure methods to investigate the effect of chemical modification at the C5 position of cytosine. A series of experimentally motivated chemical modifications are considered, including alkyl, halogen, aromatic, fused ring, and strong σ and π...

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Detalhes bibliográficos
Main Authors: Moser, Adam, Guza, Rebecca, Tretyakova, Natalia, York, Darrin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771868/
https://ncbi.nlm.nih.gov/pubmed/19890472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00214-008-0497-5
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